Hit to Lead
Cellular Activity Evaluation
Assessing cellular activity is crucial to demonstrate the anticipated impact of the binder on the target. We offer assistance in designing cell-based potency and efficacy evaluations for therapeutic candidates, aligning with the clinical mechanism of action (MoA). Our services include:
Selection of appropriate cell lines
Facilitation of cellular delivery of candidates
Conducting robust functional assays
Figure 1
Proximate biomarker semi-quantification by WB
Figure 2
PPathway activation shown by HiBiT tagged
endogenous protein quantification
Figure 3
Gene expression level or DNA copy
# comparison by qPCR
Figure 4
